Monthly
Issues
2003: March; April,
May, June, July, August, September, October, November, December
2004: January,
February, March, April, May, June, July, August, September, October, November, December
2005: January, February, March, April, May, June, July, August, September, October, November,
December
2006: January, February
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Special
Issues
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2003 EASL Meeting Highlights
2003 Clinical Experts Panel Meeting
Highlights
2004 AASLD Single
Topic Meeting: New Directions in the
Treatment of Hepatitis B
2004 EASL Meeting Highlights
2005 DDW Abstract Highlights
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Topic
Listing
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REVIEWS
§
Antiviral prophylaxis of
HBV carriers who receive immunosuppressive or cytotoxic chemotherapy
§
Antiviral
therapy for prevention of perinatal HBV transmission
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Chronic hepatitis B and
kidney transplantation
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Coinfection with hepatitis B
virus and human immunodeficiency virus
§
HBsAg seroclearance:
Outcomes in Chinese patients
§
Healthcare workers who
are chronically infected with hepatitis B virus
§
Hepatitis B Vaccine
Nonresponse
§
Hepatitis B virus (HBV)
DNA levels and hepatocellular carcinoma
§
Noninvasive surrogate
markers of hepatitis B virus (HBV) fibrosis
§
Treatment of chronic
hepatitis B in the human immunodeficiency virus (HIV)-infected patient
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ACUTE
SELF-LIMITED HBV INFECTION
§
Long
term outcomes
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ACUTE
EXACERBATION OF HBV INFECTION
§
Population
study of spontaneous HBeAg seroconversion
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ADEFOVIR
DIPIVOXIL
§
Adefovir dipivoxil therapy
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Adefovir resistance: Association with viral rebound and hepatic
decompensation
§
Development of an HBV polymerase mutation and clinical resistance
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Genotype and viral
response
§
Resistance surveillance
§
Results of treatment in lamivudine-resistant HBV
infection
§
Treatment
of HBeAg-negative chronic hepatitis B
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Treatment
of HBeAg-positive chronic hepatitis B
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ANTIBODY TO HEPATITIS B SURFACE ANTIGEN
(Anti-HBs)
§
Development of anti-HBs
after liver transplantation
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ANTIVIRAL THERAPY
§
Treatment of hepatitis B and
C dual infection
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BIOCHEMICAL MARKERS IN HBV PATIENTS
§
Prediction of histological lesions
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CHILDHOOD CHRONIC HBV
•
Current therapeutic approaches
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COINFECTION WITH HEPATITIS B AND HUMAN
IMMUNODEFICIENCY VIRUS
§
Adefovir
dipivoxil therapy for HBV/human immunodeficiency virus–1 (HIV-1)
coinfection
§
Impact of HBV coinfection on
outcomes of HIV patients
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EPIDEMIOLOGY
§
Changes
in a US community
§
Genotype and precore/core variants
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Healthcare-related viral
hepatitis transmission
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HBeAg
§
Correlation with serum HBV
DNA levels
§
Different mechanisms of
HBeAg seroconversion
§
Meaning of HBeAg and
significance of HBV levels
§
Long-term adefovir
dipivoxil therapy in HBeAg negative patients
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Long-term lamivudine
therapy in HBeAg negative patients
§
Peginterferon alfa-2a vs
lamivudine in HBeAg positive patients
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HBsAg
§
Maternal
HBsAg carrier status and pregnancy outcomes
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HBV-Associated Polyarteritis Nodosa
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Clinical characteristics and outcome
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HBV GENOTYPE TESTING
§
Topic Review: Research tool
or ready for “prime time”
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HBV REACTIVATION
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HBV VACCINATION
§
Hepatitis A and B vaccination:
Adherence to guidelines
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Lack of association with multiple sclerosis
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Long-term follow-up of a randomized trial
§
Need for boosters and
significance of HBsAg escape mutants
§
Newborn vaccination program in Taiwan
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Protection
after 15 years of follow-up
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HBV REPLICATION
§
Covalently closed circular DNA (cccDNA)
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HBV-RELATED ACUTE LIVER FAILURE
§
Virologic characteristics
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hbv transmission
§
HBV
DNA levels in serum, saliva, and urine
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Laboratory-based screening
of health care workers
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HEPATOCELLULAR CARCINOMA
§
Association with HBV DNA level
and genotype
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Effectiveness of prophylactic lamivudine administration
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HBV mode of transmission
§
HBV reactivation
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Occult HBV as a possible risk factor
for HCC
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Prospective study of Taiwanese children
with chronic HBV infection
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Role of reproductive factors
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Risk of HBV exacerbation after transcatheter arterial
chemoembolization
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Woodchuck hepatitis virus (WHV) animal model and N-myc rearrangements
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IMMUNOPROPHYLAXIS
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Long-term results following liver
transplantation
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Interferon Therapy
§
A study of individualized
therapy
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Impact on liver fibrosis
progression
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Long-term
follow-up
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Long-term suppression
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Peginterferon alfa-2b alone
or with lamivudine in patients with HBeAg-positive chronic hepatitis B
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Staggered regimen of peginterferon alfa-2b and lamivudine in
patients with HBeAg-positive chronic hepatitis B
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Lamivudine therapy
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Compassionate use
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Determinants for sustained response
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Durability of response
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Early therapy for HBV
patients undergoing chemotherapy is superior
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Extended treatment following seroconversion
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In
hepatic decompensation
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Histological outcomes
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LAM-containing therapy for
IFN nonresponders
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LAM vs. LAM + hepatitis B
immune globulin (HBIg) to prevent post-transplant HBV recurrence
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Treatment of patients with advanced liver disease
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Tenofovir disoproxil treatment
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Long-term follow-up of peginterferon and lamivudine combination
therapy
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Long-term safety
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Long-term treatment enhances durability of HBeAg loss
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Results of 2 years of treatment in patients with HBeAg-negative HBV
infection
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Transient
restoration of antiviral T-cell responses
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Treatment of acute, severe hepatitis B
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Treatment of children
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LAMIVUDINE RESISTANT hbv
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Comparison of adefovir and tenofovir
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Immunoglobulin M (IgM) antibody to
hepatitis B core antigen (anti-HBc) predicts poor response to lamivudine
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Timing of adefovir dipivoxil
(ADV) therapy for lamivudine-resistant hepatitis B virus
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LIVER TRANSPLANTATION
§
Adjuvant hepatitis B vaccine
§
HBV vaccine permits withdrawal of HBIG prophylaxis
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Improved outcome
§
Outcomes of HCV antibody-positive and
hepatitis B core antibody-positive grafts
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Prevention
of HBV reinfection after liver transplantation
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Prophylaxis of HBV recurrence
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MECHANISMS OF CHRONIC hbv INFECTION
§
Defective dendritic cell
-T cell interaction
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NATURAL HISTORY OF HBV INFECTION
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Cohort study in northern Greece
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Follow-up of patients from an early stage of HBV infection
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Genotype C vs genotype B infection
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NEW THERAPEUTIC AGENTS
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Analysis of long-term
emtricitabine trials
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Dose-escalating trial
of clevudine
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Phase II dose-finding
study of emtricitabine
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Telbivudine trial
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NON-INVASIVE TESTS IN HBV PATIENTS
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13C-caffeine breath test
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FT-AT
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Noninvasive model to
predict significant fibrosis
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NOSOCOMIAL HBV INFECTION
§
HBV and HCV infection in a
pediatric ward
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NUCLEIC
ACID TESTING (NAT) FOR HBV INFECTION
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Technological improvement
and automation
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OCCULT
HBV INFECTION
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Occult HBV in hemodialysis patients
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PEDIATRIC
CHRONIC HBV INFECTION
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Predictors of virological response
to lamivudine therapy
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PEDIATRIC
FULMINANT HEPATIC FAILURE
§
Follow-up 15 years after
universal hepatitis B vaccination
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PEGINTERFERON
(PEG-IFN) ALFA-2A THERAPY
§
First report on treatment of
chronic hepatitis B
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Peginterferon alfa-2a
versus lamivudine in HBeAg-negative patients
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PERINATAL
TRANSMISSION OF HBV
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Analysis of HBV DNA levels and HBeAg titers in Chinese mothers and
their babies
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OUTCOME
OF HBV THERAPY
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Durability of
treatment-induced HBeAg seroconversion
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PROGNOSTIC
FACTORS
§
Prognostic
determinants in Asian patients with chronic HBV
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Relation
of HBV flares to treatment response
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Risk factors for the development of
complications in Asian HBV patients
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The influence of genotype
on virologic outcomes
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RENAL
TRANSPLANTATION
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HBV in renal transplant
recipients
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RISK
FACTORS FOR HBV REACTIVATION
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Cancer patients
undergoing cytotoxic chemotherapy
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Occurrence during chemotherapy
for hematologic malignancies
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Occurrence after
infliximab therapy for Crohn's disease
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Association with
disappearance of anti-HBs following allogeneic hematopoietic stem cell
transplantation
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RANDOMIZED
STUDIES
§
Dose-finding study of
once-daily oral telbivudine in HBeAg-positive patients with chronic HBV
infection
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Entecavir
dose-ranging study
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Steroid-free chemotherapy
and the risk of HBV reactivation
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Serum HBV DNA as marker
for treatment efficacy
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SUPERINFECTION
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Impact of acute hepatitis C in patients with chronic HBV infection
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THYMALFASIN
§
Efficacy and safety of thymalfasin
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TRANSPLANTATION
§
Subclinical reactivation of HBV
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TREATMENT
GUIDELINES
§
Recommended updates
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